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This disease has a ten-fold increase in the risk of occurrence in smokers than in non-smokers, with the treatment being less effective too

Topical antiviral creams or patches: These contain antiviral agents like acyclovir or penciclovir, which work by inhibiting the replication of the virus that causes cold sores

Cirrhosis gradually causes scar tissue to gradually replace liver cells

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[31] Sales and popularity [edit] In 2015, it was the most popular e-cigarette in the United States with 33% market share in Nielsen-tracked channels